Pantethine is a naturally occurring compound and is the active form of pantothenic acid. Structurally, pantethine is a disulfide form of pantothenic acid with two cysteamine bridging groups. In the body, it is metabolized to coenzyme A.
According to secondary sources, supplemental forms of pantethine are not stable and the product requires refrigeration. For this reason, vitamin B5 supplements are usually taken as calcium pantothenate.
Research has demonstrated that pantethine, when taken orally, may be used for lowering cholesterol. It has also been used for lowering cardiovascular risk, improving energy, and improving adrenal function. However, adequate evidence in support of uses other than lipid lowering is lacking at this time.
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